行甲状腺全切除和次全切除术对甲状腺癌的患者治疗效果及安全性比较

Comparison of the Efficacy and Safety of Total Thyroidectomy and Subtotal Thyroidectomy in the Treatment of Thyroid Carcinoma

目的探究对甲状腺癌患者行甲状腺全切除术和次全切除术的治疗效果及其安全性。方法选择佳木斯市中心医院就诊的甲状腺癌患者60例为研究对象,按照患者自身意愿将其分为A组和B组,每组各30例。A组患者采用甲状腺全切除术,B组患者采用甲状腺次全切除术。对两组方案的应用效果进行比较。结果A组患者治疗后的甲状旁腺素、血清钙离子水平均低于B组;A组术后并发症发生率为36.67%,高于B组并发症发生率(10.00%);手术后1年,A组患者复发率为6.66%,低于B组复发率(26.67%),差异有统计学意义(P<0.05)。结论甲状腺全切除术与次全切除术均可获得较好疗效,全切除术治疗更为彻底,复发率低,远期疗效较好,但对甲状旁腺的损伤较大,术后并发症发生率较高,在临床治疗中可根据患者的具体情况选择适合的手术方式。

Objective To investigate the efficacy and safety of total thyroidectomy and subtotal thyroidectomy in patients with thyroid cancer.Methods 60 patients with thyroid carcinoma were divided into group A and group B received according to their own wishes,with 30 cases in each group.Group A received total thyroidectomy,and group Breceivecl subtotal thyroidectomy.The application effects of the two groups were compared.Results The levels of parathyroid hormone and serum calcium in group A were lower than those in group B.The incidence of postoperative complications in group A was 36.67%,which was higher than that in group B (10.00%).The recurrence rate of group A was 6.66%,which was lower than that of group B(26.67%).The difference between the two groups was significant(P < 0.05).Conclusion Total thyroidectomy and subtotal thyroidectomy have better curative effect.Total thyroidectomy is more complete,the recurrence rate is low,the long-term effect is better,but the injury of parathyroid gland is more serious,and the incidence of postoperative complications is higher.In the clinical treatment,the suitable operation method can be chosen according to the patient’s specific condition.