农业劳动者高尿酸血症与非冻结性冷伤的横断面研究

Cross-sectional survey between hyperuricemia and non-frozen cold wounds among agricultural workers

目的探讨农业劳动者高尿酸血症与非冻结性冷伤(冻疮)的相关性,为采取防护措施提供依据。方法于2016年10月~2017年9月,采用横断面调查方法,选取浙江省开化县某乡镇3 107名成年农业劳动者为研究对象,将其中有高尿酸血症371人列为观察组,无高尿酸血症2 736人列为对照组,记录冬季非冻结性冷伤发生情况,进行数据处理和分析,计算高尿酸血症者发生冻疮的PR及95%CI值。结果非冻结性冷伤患者总数为195例,患病率为6.28%。观察组非冻结性冷伤55例(14.82%);对照组非冻结性冷伤140例(5.12%),差异有统计学意义(χ2=52.342,P<0.05);观察组的非冻结性冷伤患病率高(PR=2.897,95%CI:2.163~3.881)。结论高尿酸血症可能是发生非冻结性冷伤的危险因素之一,有高尿酸血症的农业劳动者在冬季更应注意御寒保暖和预防非冻结性冷伤。

Objective To investigate the correlation between hyperuricemia and non-frozen cold wounds (chilblains) in agricultural workers of a township for prevention measures. Methods From October 2016 to September 2017, a cross sectional study was applied to 3107 agricultural workers of a township in kaihua county, zhejiang province, of which 371 people with hyperuricemia were observed as the objective group and of which 2 736 people without hyperuricemia as the control group. The data of the occurrence of non-frozen cold wounds (chilblains) in winter among the objective group and the control group were gathered. The descriptive statistics was carried out with the prevalence ratio (PR) of chilblains and 95% confidence intervals of those agricultural workers with hyperuricemia. Results The prevalence rate was 11.94% and 371 cases with hyperuricemia among 3107 agricultural workers of a township. The total number of cases of non-frozen cold wounds(chilblains) was 195 cases and the prevalence rate was 6.28% with Chilblains among 3 107 agricultural workers of a township. The total of 55 cases with chilblains(14.82%) among the objective group, and 140 cases with chilblains (5.12%) were found among the control group (χ2=52.342, P<0.05). The objective group had a high prevalence of chilblains. The prevalence ratio (PR) of chilblains was 2.897 (95% CI 2.163-3.881). Conclusion Hyperuricemia may be a risk factor for non-frozen cold wounds (chilblains). Those agricultural workers with hyperuricemia should pay more attention to keep warm and prevent non-frozen cold wounds (chilblains)in winter.