摘要
A族链球菌(GAS)又称为化脓性链球菌(S.pyogenes),是一种全球范围内的人类致病菌,亦是引起呼吸道感染的常见致病菌。GAS表面蛋白,作为GAS重要组成部分,在GAS致病与诱导机体免疫应答方面发挥着关键作用。现就各类GAS的表面蛋白与宿主相互作用机制作一综述。
Streptococcus A (group A streptococcus, GAS) is also known as Suppurative Streptococcus (S.Pyogenes), a worldwide human pathogen.It is also a common pathogen causing respiratory tract infections.GAS surface protein, as an important part of GAS, plays a key role in GAS pathogenesis and inducing the immune response of the body.Therefore, this paper reviews the interaction mechanism between surface protein and host in GAS.
作者
于淼
何其磊
李晓
张鹏翔
马翠卿
Yu Miao;He Qilei;Li Xiao;Zhang Pengxiang;Ma Cuiqing(Department of Immunology, School of Basic Medical Science, Hebei Medical University, Key Laboratory of Immune Mechanism and Intervention on Serious Disease in Hebei Province, Shijiazhuang 050017, China)
出处
《国际呼吸杂志》
2019年第15期1176-1181,共6页
International Journal of Respiration
基金
河北省自然科学基金(H2016206516)
河北省教育厅重点课题(ZD2018001).
关键词
链球菌
酿脓
膜蛋白质类
致病机制
Streptococcus pyogenes
Membrane proteins
Pathogenic mechanism
