微小RNA在支气管肺发育不良发病机制中的研究进展

Research progress of microRNA in the pathogenesis of bronchopulmonary dysplasia

支气管肺发育不良是早产儿相关的常见并发症之一,是引起早产儿致残甚至死亡的主要原因之一,尚缺乏特效的防治措施.近几年分子生物学研究发现,在支气管肺发育不良的发生发展过程中微小RNA起重要作用.本文就微小RNA在支气管肺发育不良发病机制中的研究进行综述,为寻找新的诊疗方法奠定一定的理论基础.

Bronchopulmonary dysplasia is one of the common complications related to premature infants.It is one of the main causes of disability or death in premature infants.There is still lack of specific prevention and treatment measures.In recent years, molecular biology studies have found that micro-RNA plays an important role in the occurrence and development of bronchopulmonary dysplasia.In this paper, the research of micro-RNA in the pathogenesis of bronchopulmonary dysplasia is reviewed, and the theoretical basis is laid for the search for new diagnosis and treatment methods.