盐酸氨溴索对慢性阻塞性肺疾病急性加重期的疗效分析

Clinical analysis of the efficacy of ambroxol hydrochloride in the treatment of acute exacerbation of chronic obstructive pulmonary disease

目的探讨分析盐酸氨溴索对治疗慢性阻塞性肺疾病(COPD)急性加重期的临床疗效。方法选择2015年6月—2018年12月本院收治的60例COPD患者为研究对象,将其随机分为观察组和对照组两组,每组各30例。对照组进行常规基础方案的治疗;观察组则在常规方案的基础上应用静脉滴注盐酸氨溴索的方法进行治疗,每日2次,每次30 mg。结果两组患者治疗后不良反应发生率差异无统计学意义(P>0.05)。观察组患者相较于对照组患者临床症状缓解更快,临床治疗有效率高于对照组患者,差异具有统计学意义(P<0.05)。结论盐酸氨溴索明显舒缓症状并有效缩短住院时间,值得应用与推广。

Objective To investigate the clinical efficacy of ambroxol hydrochloride in the treatment of acute exacerbation of chronic obstructive pulmonary disease( COPD). Methods To investigate the clinical efficacy of ambroxol hydrochloride in the treatment of acute exacerbation of chronic obstructive pulmonary disease( COPD).Results There was no significant difference in the incidence of clinical adverse reactions between the two groups(P>0.05). Compared with the control group,the patients in the observation group had faster clinical symptom relief and the higher clinical treatment efficiency. The difference was statistically significant(P<0.05).Conclusions Ambroxol hydrochloride could not only relieve symptoms,but also effectively shorten the length of hospital stay.It is worthy of application and promotion.