N末端B型利钠肽原和尿酸水平在肺血栓栓塞症和慢性心力衰竭诊断中的评价

Evaluation of N-terminal B-type Natriuretic Peptide and Uric acid Levels in the diagnosis of Pulmonary Thromboembolism and Chronic Heart Failure

目的探讨N末端B型利钠肽原和尿酸水平在肺血栓栓塞症(PTE)和慢性心力衰竭(CHF)患者中的差异。方法选自2013年05月至2018年06月来我院就诊的急性呼吸困难患者94例,后明确诊断将患者分为PTE组35例和CHF组59例,所有患者均进行N末端B型利钠肽原(NT-proBNP)、血尿酸(UA)水平的检测。结果 CHF组NT-proBNP、UA水平(6854.4±2143.3)pg/ml、(482.1±89.4)umol/L显著高于PTE组(2436.8±851.8)pg/ml、(324.5±88.4)umol/L,差异有统计学意义,P<0.05。结论 NT-proBNP、血UA水平可能作为PTE与CHF鉴别诊断的参考指标。

Objective To investigate the difference between N-terminal B-type natriuretic peptide and uric acid levels in patients with pulmonary thromboembolism(PTE)and chronic heart failure(CHF).Methods 94 patients with acute dyspnea from May 2013 to June 2018 were selected,and the patients were divided into 35 cases in PTE Group and 59 cases in CHF group,and all patients were detected by N-terminal B-type natriuretic peptide original(NT-proBNP)and serum uric acid(UA)level.Results CHF group NT-proBNP,UA level(6854.4±2143.3)pg/ml,(482.1±89.4)umol/L significantly higher than PTE Group(2436.8±851.8)pg/ml,(324.5±88.4)umol/l,The difference was statistically significant(P<0.05).Conclusion The level of NT-proBNP and blood UA may be used as a reference index for the differential diagnosis of PTE and CHF.