B族链球菌筛查对妊娠结局及新生儿的影响

Effect of Group B Streptococcus Screening on Pregnancy Outcome and Neonates

目的分析B族链球菌筛查工作对于妊娠结局与新生儿的预后影响。方法研究对象选择2017年1月-2017年12月在本院进行产检且行GBS监测的孕妇300例,分为筛查阳性组与筛查阴性组,每组150例。两组孕妇均接受抗生素静脉注射,然后对比分析孕妇的妊娠结局与新生儿并发症产生情况,判定B族链球菌筛查的具体作用。结果研究结果表明,孕妇出现宫内感染、产后出血等症状的比例中,阴性组普遍较低,总体例数对比为16例与4例;此外在新生儿情况方面,阴性组新生儿出现并发症的几率同样较低,例数对比为10例与3例。结果证明了B族链球菌筛查工作的必要性,数据差异具有统计学意义(P <0.05)。结论 GBS感染会显著提升孕妇与新生儿出现感染、不良反应的发生率,因此对孕晚期的孕妇进行B族链球菌筛查可以及时采取有效的治疗干预措施,减少母婴不良反应的出现。

Objective To analyze the effect of group B streptococcus screening on pregnancy outcome and neonatal prognosis. Methods 300 pregnant women who underwent prenatal examination and underwent GBS monitoring in the hospital from January 2017 to December 2017 were selected as subjects, which were divided into the screening positive group and the screening negative group, with 150 cases in each group. Both groups of pregnant women were received intravenous antibiotics injections,and then the pregnancy outcome of pregnant women and neonatal complications were compared and analyzed to determine the specific role of group B streptococcus screening. Results The results showed that the proportion of intrauterine infection and postpartum hemorrhage in pregnant women was generally lower in the negative group, and the overall number of cases was 16 cases and 4 cases. In addition for neonatal condition, the incidence of neonatal complications in the negative group was also lower,with the number of cases compared to 10 and 3. The results demonstrated the necessity of group B streptococcus screening, and the data difference was statistically significant(P < 0.05). Conclusion GBS infection can significantly increase the incidence of infection and adverse reactions in pregnant women and newborns. Therefore, group B streptococcus screening for pregnant women in the third trimester of pregnancy can timely take effective treatment and intervention measures to reduce the occurrence of adverse reactions in mothers and infants.