不同质子泵抑制剂治疗Hp阳性消化性溃疡效果

Treatment of Hp-Positive Peptic Ulcer With Different Proton Pump Inhibitors

目的探究Hp阳性消化性溃疡患者在进行治疗临床治疗过程中,选择不同质子泵抑制剂与克拉霉素、阿莫西林联合治疗的效果对比。方法本文对本院收治的76例患者进行分组对比研究,入选者均为Hp阳性消化性溃疡的患者,患者病例选择时间2016年6月-2018年12月,设为38例对照组的患者治疗药物选择泮托拉唑、克拉霉素以及阿莫西林,设为38例观察组的患者治疗药物选择埃索美拉唑、克拉霉素以及阿莫西林。结果观察组消化性溃疡患者进行治疗后,总有效率92.10%,Hp根除率94.74%,腹痛缓解率为92.11%,对照组消化性溃疡患者进行治疗后,总有效率73.69%,Hp根除率78.95%,腹痛缓解率为71.05%,经统计对比可知P <0.05;观察组5.26%的患者出现不良反应,对照组13.15%的患者出现不良反应,经统计对比可知P> 0.05。结论 Hp阳性消化性溃疡患者在治疗过程中,医务人员采用如下药物实施治疗,即埃索美拉唑、克拉霉素以及阿莫西林,效果确切。

Objective To investigate the effect of different proton pump inhibitors combined with clarithromycin and amoxicillin in the treatment of patients with Hp-positive peptic ulcer. Methods A total of 76 patients in the hospital were enrolled in a comparative study. All patients were enrolled in patients with Hp-positive peptic ulcer. Patient case selection time June2016-December 2018, set as 38 patients in the control group Therapeutic drugs were selected from pantoprazole, clarithromycin, and amoxicillin,and 38 patients in the observation group were treated with esomeprazole,clarithromycin, and amoxicillin. Results After treatment, the total effective rate was 92.10%, the eradication rate of Hp was 94.74%, and the relief rate of abdominal pain was 92.11% in the observation group. After treatment,the total effective rate was 73.69%, the eradication rate of Hp was 78.95%,and the relief rate of abdominal pain was 71.05% in the control group.Statistical comparison showed that P < 0.05;5.26% of the patients in the observation group had adverse reactions, and 13.15% of the patients in the control group had adverse reactions. According to statistics, P > 0.05.Conclusion After admission to patients with Hp-positive peptic ulcer,medical staff were treated with the following drugs, namely esomeprazole,clarithromycin and amoxicillin. The effect was exact.