化学发光免疫法在甲状腺肿瘤生物标志物检测中的应用效果分析

Analysis of the effect of Chemiluminescence Immunoassay in the Detection of Thyroid Tumor Biomarkers

本文利用化学发光免疫法对医院同期收治的甲状腺肿瘤患者进行研究,以42例甲状腺肿瘤患者为观察组,以42例同期在医院进行体检的健康人员为对照组来进行研究,分别对观察组和对照组采用化学发光免疫法和放射免疫法来检测人员血浆中的甲状腺球蛋白的浓度、尿CK19指标,从而比较两种方法的灵敏度和特异性。检测结果表明,利用化学发光免疫法检测的甲状腺球蛋白浓度指标要明显高于放射免疫法,且假阳性和假阴性的检出率也优于放射免疫法,同时与对照组相比,尿CK19指标的检测也非常明显。

In this paper, 42 patients with thyroid tumor were studied by chemiluminescence immunoassay. 42 patients with thyroid tumor were taken as observation group and 42 healthy people who were examined in hospital at the same time as control group. Chemiluminescence immunoassay and radioimmunity were used to detect the blood of the observation group and the control group, respectively. The concentration of thyroglobulin in plasma and urine CK19 index were compared to compare the sensitivity and specificity of the two methods. The results showed that the concentration of thyroglobulin detected by chemiluminescence immunoassay was significantly higher than that by radioimmunity, and the detection rate of false positive and false negative was also better than that of radioimmunity, and compared with the control group, the detection of urinary CK19 index was also very obvious.