子宫动脉栓塞术对产后出血患者雌二醇黄体生成素和卵泡刺激素水平的影响

Effect of Uterine Artery Embolization on Estradiol, Luteinizing Hormone and Follicle Stimulating Hormone Levels in Patients with Postpartum Hemorrhage

目的:分析探讨子宫动脉栓塞术对产后出血患者雌二醇、黄体生成素和卵泡刺激素水平的影响.方法:选取我院于2016年1月至2018年12月期间收治的60例产后出血患者,根据患者是否接受子宫动脉栓塞术将其划分为甲乙两组,其中甲组患者均采取子宫动脉栓塞术进行治疗,而乙组患者则采用非子宫动脉栓塞术进行治疗.记录两组患者的24h内产后出血量和住院时间,比较两组患者的ICU入住率、子宫切除率、产褥感染率、产后出血率等指标,并分析两组患者治疗前后的促卵泡成熟激素和促黄体生成素、雌二醇的水平变化情况.结果:两组患者的住院时间并无明显差异(t=0.625,P>0.05);甲患者的24h内产后出血量为(1039.28±53.44)mL,显著低于乙组患者的(2734.39±43.29)mL(t=6.283,P<0.05).两组患者的产褥感染率并无明显差异(P>0.05);甲组患者的ICU入住率和子宫切除率以及产后出血率分别为43.75%和0、46.88%,分别低于乙组患者的78.57%和7.14%、85.71%(t=10.282,t=5.394,t=11.283,均P<0.05).两组患者治疗前的促卵泡成熟激素和促黄体生成素、雌二醇的水平均无明显差异(均P>0.05);治疗后甲组患者的促卵泡成熟激素和促黄体生成素、雌二醇的水平均显著优于乙组患者(t=3.293,t=4.383,t=5.384,均P<0.05).结论:对于产后出血患者采用子宫动脉栓塞术进行治疗能够有效改善其治疗效果,并且不会对患者的卵巢功能以及促卵泡成熟激素和促黄体生成素、雌二醇的水平造成较大影响,值得在临床上推广运用.

Objective: To investigate the effects of uterine artery embolization on the levels of estradiol luteinizing hormone and follicle stimulating hormone in postpartum hemorrhage patients. Methods: 60 patients with postpartum hemorrhage admitted to our hospital from January 2016 to December 2018 were divided into two groups according to whether the patients received uterine artery embolization. The patients in group A were treated with uterine artery embolization, while those in group B were treated with non-uterine artery embolization. The amount of postpartum hemorrhage and hospital stay in 24 hours were recorded. The ICU occupancy rate, hysterectomy rate, puerperal infection rate and postpartum hemorrhage rate were compared between the two groups. The changes of follicle-stimulating hormone, luteinizing hormone and estradiol levels before and after treatment were analyzed. Results: There was no significant difference in hospital stay between the two groups (t=0.625, P>0.05). Postpartum hemorrhage within 24 hours in group a was (1039.28±53.44) ml, significantly lower than that in group b (2734.39±43.29) ml (t=6.283, P<0.05). There was no significant difference in puerperal infection rate between the two groups (P>0.05). The ICU occupancy rate, uterine resection rate and postpartum hemorrhage rate in group a were 43.75%, 0 and 46.88%, respectively, lower than those in group b 78.57%, 7.14% and 85.71%(t=10.282, t=5.394, t=11.283, all P<0.05). There were no significant differences in the levels of follicular maturation hormone, luteinizing hormone and estradiol between the two groups before treatment (all P>0.05). After treatment, the levels of follicle-stimulating hormone, luteinizing hormone and estradiol in group a were significantly higher than those in group b (t=3.293, t=4.383, t=5.384, all P<0.05). Conclusion: Uterine artery embolization for postpartum hemorrhage patients can effectively improve the therapeutic effect, and will not have a greater impact on ovarian function, follicle-stimulating hormone, luteinizing hormone and estradiol levels. It is worthy of clinical application.