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消化系统肿瘤中TGFBI研究进展

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摘要 消化系统恶性肿瘤发病率高,严重危害人类健康。转化生长因子β诱导基因(transforming growth factorβinduced gene,TGFBI)参与肿瘤细胞调节、分化、转移及诱发上皮细胞-间质转化,其在不同肿瘤中表现为启动或抑制肿瘤发生、发展的双重生物学特性。TGFBI有望成为消化系统肿瘤早期诊断、靶向治疗及评估预后的标志物,该文现就TGFBI异常表达的致癌机制及其在消化系统肿瘤中的研究进展作一综述。
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2019年第7期816-819,共4页 Chinese Journal of Clinical and Experimental Pathology
基金 青海省科技厅自然科学基金(2017-ZJ-913)
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  • 1陈晓鹏,刘颖斌,史良会.串珠聚糖在肝细胞癌的分布及其免疫组化阳性判断标准的初探[J].东南大学学报(医学版),2005,24(2):85-89. 被引量:2
  • 2Jemal A,Siegel R,Ward E,et al.Cancer statistics,2008[J].CA Can-cer J Clin,2008,58 (2):71-96.
  • 3Jemal A,Siegel R,Ward E,et al.Cancer statistics,2009[J].CA Can-cer J Clin,2009,59(4):225-249.
  • 4Vincent A,Herman J,Schulick R,et al.Pancreatic cancer[J].Lan-cet,2011,378(9791):607-620.
  • 5Skonier J,Neubauer M,Madisen L,et al.cDNA cloning and se-quence analysis of beta ig-h3,a novel gene induced in a human ad-enocarcinoma cell line after treatment with transforming growth fac-tor-beta[J].DNA Cell Biol,1992,11(7):511-522.
  • 6Clout NJ,Tisi D,Hohenester E.Novel fold revealed by the struc-ture of a FAS1 domain pair from the insect cell adhesion molecule fasciclin I[J].Structure,2003,11(2):197-203.
  • 7Runager K,Enghild JJ,Klintworth GK.Focus on molecules:Trans-forming growth factor beta induced protein (TGFBIp)[J].Exp Eye Res,2008,87(4):298-299.
  • 8Runager K,García-Castellanos R,Valnickova Z,et al.Purifica-tion,crystallization and preliminary X-ray diffraction of wild-type and mutant recombinant human transforming growth factor be-ta-induced protein (TGFBIp)[J].Acta Crystallogr Sect F Struct Biol Cryst Commun,2009,65(Pt 3):299-303.
  • 9Kim HJ,Kim PK,Bae SM,et al.Transforming growth factor-be-ta-induced protein (TGFBIp/beta ig-h3) activates platelets and pro-motes thrombogenesis[J].Blood,2009,114(25):5206-5215.
  • 10Wen G,Partridge MA,Li B,et al.TGFBI expression reduces in vi-tro and in vivo metastatic potential of lung and breast tumor cells[J].Cancer Lett,2011,308(1):23-32.

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