摘要
恙虫病是由恙螨叮咬,感染恙虫病东方体引起的一种自然疫源性传染病。它常常以急性发热、常伴皮疹或焦痂、对抗生素治疗敏感为特征,若救治不及时可能导致严重的多器官衰竭甚至高达70%的死亡率。延迟救治是导致恙虫病患者高死亡率的主要原因。恙虫病往往无典型症状,易与其他地区性疾病混淆,且临床诊断手段相对落后,易被忽视。本文针对恙虫病的病原体、临床诊治特点及防控策略进行文献综述,以加强公众和临床医生对恙虫病的认识,提高该疾病的诊断水平,降低恙虫病的重症率和死亡率。
Scrub typhus is an infectious disease caused by Orientia tsutsugamushi, transmitted by the bites of chigger mites, and usually characterized by acute fever, skin rash or scab, and sensitivity to antibiotics. Scrub typhus can result in severe multiorgan failure with a case fatality rate up to 70% without timely and appropriate treatment. Delayed treatment is the main cause of high mortality in patients with scrub typhus. Scrub typhus often has no typical symptoms, is easy to be confused with other regional diseases, and the clinical diagnostic methods are relatively backward and easy to be ignored. In present paper, the literature review dealt with the pathogen, clinical diagnosis and treatment characteristics and prevention and control strategies of scrub typhus is carried out in order to strengthen the public and clinicians’ understanding of scrub typhus, improve the diagnosis level of the disease, and reduce the rate and mortality of scrub typhus.
作者
栗绍刚
郭东星
李静宜
李丹
吴赵永
LI Shao-Gang;GUO Dong-Xing;LI Jing-Yi;LI Dan;WU Zhao-Yong(Beijing Key Laboratory for Research on Prevention and Treatment of Tropical Diseases,Beijing Tropical Medicine Research Institute, Beijing Friendship Hospital,Capital Medical University, Beijing 100050, China)
出处
《寄生虫与医学昆虫学报》
CAS
2019年第2期118-123,共6页
Acta Parasitologica et Medica Entomologica Sinica
关键词
恙虫病
恙虫病东方体
临床特征
诊断治疗
预防
Scrub typhus
Orientia tsutsugamushi
Clinical features
Diagnosis
Treatment
Prevention
