米非司酮治疗子宫内膜异位症临床效果探讨

Clinical Effect of Mifepristone in the Treatment of Endometriosis

目的分析米非司酮治疗子宫内膜异位症临床效果。方法选取该院于2017年10月-2018年10月收治的50例子宫内膜异位症患者作为实验对象,抛硬币方式随机分为实验组与对照组,各组25例。对照组予以孕三烯酮治疗,实验组予以米非司酮治疗。治疗3个疗程后,对比两组临床症状变化,分析两组治疗前后的血清激素水平。结果治疗前,两组患者的血清卵泡刺激素、雌二醇、促黄体生成素水平差异无统计学意义(P>0.05);实验组患者治疗后的FSH、LH水平低于对照组(t=7.081、6.419,P<0.05);E2水平高于对照组(χ^2=8.307,P<0.05);实验组治疗总有效率为92.00%,高于对照组(χ^2=10.076,P<0.05)。结论米非司酮治疗子宫内膜异位症可以更好地调节患者的激素水平,临床治疗效果更佳,值得应用。

Objective To analyze the clinical effect of mifepristone in the treatment of endometriosis.Methods A total of 50 patients with endometriosis admitted to our hospital from October 2017 to October 2018 were randomly divided into experimental group and control group,with 25 cases in each group.The control group was treated with gestrinone and the experimental group was treated with mifepristone.After 3 courses of treatment,the clinical symptoms of the two groups were compared,and serum hormone levels before and after treatment were analyzed.Results Before treatment,the levels of serum follicle stimulating hormone,estradiol and luteinizing hormone in the two groups were not statistically significant(P>0.05).The levels of FSH and LH in the experimental group were lower than those in the control group(t=7.081,6.419,P<0.05);E2 level was higher than the control group(t=8.307,P<0.05);the total effective rate of the experimental group was 92.00%,higher than the control group(χ^2=10.076,P<0.05).Conclusion Mifepristone treatment of endometriosis can better regulate the hormone level of patients,and the clinical treatment effect is better,which is worthy of application.