关注肺结核在COPD发生发展中的作用

Pulmonary tuberculosis in the development and progression of COPD

在我国慢性阻塞性肺疾病(COPD)是患病率最高、危害最大的慢性呼吸系统疾病,而肺结核是最重要的呼吸道传染病之一。研究表明肺结核是COPD的重要危险因素之一,特别是在结核高负担的国家和地区。作为COPD的关键危险因素,吸烟与结核杆菌感染之间相互影响。充分认识肺结核在COPD发生、发展中的作用,不但有助于拓宽对COPD危险因素和发病机制的认识,对于COPD的防治亦具有重要科学意义和临床意义。

Chronic obstructive pulmonary disease(COPD)is the most prevalent chronic respiratory disease in China,where pulmonary tuberculosis is also one of the most important respiratory infectious diseases.Studies have shown that pulmonary tuberculosis is an important risk factor for COPD,particularly in countries and regions with a high burden of tuberculosis.As the major risk factor for COPD,cigarette smoking interacts with tuberculous infection and impacts disease expressions.Knowledge on the role of tuberculosis in development and progression of COPD is needed for understanding of the etiology and pathogenesis of COPD beyond cigarette smoking,which is expected to provide scientific data for prevention and treatment of the disease.