奥硝唑治疗妇科肿瘤患者术后厌氧菌盆腔感染的临床研究

Clinical Study of Ornidazole in the Treatment of Postoperative Anaerobic Pelvic Infection in Patients with Gynecologic Tumors

目的观察并探讨奥硝唑治疗妇科肿瘤患者术后厌氧菌盆腔感染的临床效果。方法方便选取于2016年12月-2018年12月期间来该院就诊的妇科肿瘤患者术后厌氧菌盆腔感染患者136例,按患者就诊顺序分为对照组与实验组,人数相同各68例,实验组与对照组患者封闭给予奥硝唑治疗及常规药物治疗,观察并对比两组患者治疗痊愈时间、治疗总有效率以及不良反应发生情况。结果实验组患者治疗痊愈时间(5.41±0.76)d,显著短于对照组(7.89±1.20)d,差异有统计学意义(t=10.324 7,P<0.05)。实验组患者临床治疗有效率(97.06%)与对照组(80.88%)结果比较均显著较优,差异有统计学意义(χ^2=8.965 7,P<0.05)。实验组患者治疗后不良反应发生率(4.41%)显著低于对照组(25.00%),差异有统计学意义(χ^2=9.635 4,P<0.05)。结论在妇科肿瘤术后厌氧菌盆腔感染患者临床上应用奥硝唑治疗具有确切临床效果,能够显著缩短患者临床治疗痊愈时间,安全性较高,减少了不良反应的发生,有助于患者预后的改善及生活质量的提升,值得推广应用。

Objective To observe and explore the clinical effect of ornidazole in the treatment of postoperative anaerobic pelvic infection in patients with gynecologic tumors. Methods A total of 136 patients with gynecologic tumors who came to our hospital from December 2016 to December 2018 were convenient selected and enrolled in the anaerobic pelvic infection. The patients were divided into the control group and the experimental group according to the order of the patients.The experimental group and the control group were treated with ornidazole and conventional drug treatment. The healing time, total treatment efficiency and adverse reactions were observed and compared between the two groups. Results The healing time of the experimental group was(5.41 ±0.76) d, which was significantly shorter than that of the control group(7.89±1.20)d. The difference was statistically significant(t=10.324 7, P<0.05). The clinical treatment efficiency(97.06%) and the control group(80.88%) were significantly better in the experimental group. and the difference was statistically significant(χ^2=8.965 7, P<0.05). The incidence of adverse reactions(4.41%) in the experimental group was significantly lower than that in the control group(25.00%). The difference was statistically significant(χ^2=9.635 4, P<0.05). Conclusion The clinical application 25.00% of ornidazole in patients with anaerobic pelvic infection after gynecologic oncology has a definite clinical effect, which can significantly shorten the time of clinical treatment, safer, reduce the occurrence of adverse reactions and contribute to the prognosis of improvement and improvement of quality of life of patients, which is worth promotion and application.