小儿轮状病毒性肠炎的治疗及患儿生活质量指标评估

Treatment of Children with Rotavirus Enteritis and Assessment of Quality of Life Indicators in Children

目的探讨小儿轮状病毒性肠炎的治疗及患儿生活质量指标。方法方便选取该院2017年10月-2018年11月小儿轮状病毒性肠炎患儿74例。随机分组,常规治疗组采取常规药物治疗,综合治疗组则采取常规药物+培菲康治疗。比较两组疾病疗效;轮状病毒转阴的时间、粪便次数正常时间、呕吐消失时间、体温正常时间、恢复正常粪便形状的时间;治疗前后患儿呕吐、发热、脱水和腹泻症状积分以及生活质量指标;不良反应。结果综合治疗组疾病疗效100.00%高于常规治疗组差异有统计学意义(χ^2=8.621, P<0.05);综合治疗组轮状病毒转阴的时间、粪便次数正常时间、呕吐消失时间、体温正常时间、恢复正常粪便形状的时间(5.11±1.21)d、(4.11±1.42)d、(3.21±0.24)d、(1.21±0.11)d、(6.67±0.35)d和常规治疗组比较有优势,差异有统计学意义(t=6.815、6.807、6.021、6.245、6.255,P<0.05)。综合治疗组和常规治疗组不良反应相似,均是8.11%(χ^2=0.000,P>0.05)。治疗后综合治疗组呕吐、发热、脱水和腹泻症状积分(0.56±0.21)分、(0.78±0.13)分、(0.32±0.13)分、(0.19±0.02)分以及生活质量(90.56±3.34)分均优于常规治疗组,差异有统计学意义(t=6.067、6.821、6.079、6.225、6.222,7.033,P<0.05)。结论常规药物+培菲康治疗小儿轮状病毒性肠炎效果好,可有效改善临床症状,缩短治疗时间,并改善患儿的生活质量,安全性高。

Objective To investigate the treatment of children with rotavirus enteritis and the quality of life indicators of children. Methods Convenient selected 74 children with pediatric rotavirus enteritis from October 2017 to November 2018 in our hospital. Randomized, the conventional treatment group was treated with conventional drugs, and the general treatment group was treated with conventional drugs + Peficon. Compare the efficacy of the two groups of diseases;the time of rotavirus conversion, the normal time of fecal times, the time of vomiting disappear, the normal temperature of the body temperature, the time to restore the shape of normal feces;the scores of vomiting, fever, dehydration and diarrhea before and after treatment, and the quality of life Indicators;adverse reactions. Results The curative effect of the comprehensive treatment group was 100.00% higher than that of the conventional treatment group,the difference was statistically significant(χ^2=8.621, P<0.05). The time of rotavirus conversion, the normal time of fecal discharge, the time of vomiting disappeared,the normal temperature of the body, and the recovery of normal feces in the comprehensive treatment group of(5.11±1.21)d,(4.11±1.42)d,(3.21±0.24)d,(1.21±0.11)d,(6.67±0.35)d was superior to the conventional treatment group,the difference was statistically significant(t=6.815, 6.807, 6.021, 6.245, 6.255, P<0.05). The adverse reactions were similar in the combination treatment group and the conventional treatment group, which were 8.11%(χ^2=0.000, P >0.05). After treatment, the scores of vomiting, fever, dehydration and diarrhea in the comprehensive treatment group were(0.56±0.21)points,(0.78±0.13)points,(0.32±0.13)points, 0.19±0.02)points and the quality of life(90.56±3.34)points were better than the conventional treatment group,the difference was statistically significant(t =6.067, 6.821, 6.079, 6.225, 6.222, 7.033, P <0.05).Conclusion Conventional medicine + Peifikang is effective in treating children with rotavirus enteritis, which can effectively improve clinical symptoms, shorten treatment time, improve the quality of life of children, and have high safety.