磷酸奥司他韦联合炎琥宁治疗儿童病毒性流感的临床效果分析

Clinical Effect Analysis of Oseltamivir Phosphate Combined with Yanhuning in the Treatment of Children with Viral Influenza

目的探讨磷酸奥司他韦联合炎琥宁治疗儿童病毒性流感的临床效果。方法方便收集2016年3月-2018年12月病毒性流感的60例患儿,按随机表法分为两组,30例研究组和30例对照组,两组治疗方案均为磷酸奥司他韦口服,研究组加用炎琥宁治疗。对比①研究组和对照组体温正常时间、咳嗽好转时间及咳痰好转时间。②研究组和对照组儿童病毒性流感治疗疗效。③研究组和对照组治疗期间并发症发生情况。结果研究组和对照组体温正常时间、咳嗽好转时间及咳痰好转时间明显短于对照组,两组结果分别为[(2.34±0.85)d、(2.64±0.97)d、(2.12±0.87)d] vs[(3.69±1.15) d、(3.97±1.32)d、(3.66±1.82)d],比较差异有统计学意义(t=5.695、7.415、5.397,P<0.05);研究组和对照组病毒性流感治疗疗效分别为100.00%、86.67%,结果比较差异有统计学意义(χ^2=5.377,P<0.05);研究组治疗期间未发生并发症,对照组住院期间发生1例支气管炎、1例肺炎,研究组和对照组治疗期间并发症发生率分别为0.00%、6.67%,比较差异有统计学意义(χ^2=6.983,P<0.05)。结论磷酸奥司他韦联合炎琥宁治疗儿童病毒性流感疗效肯定,能够明显改善患者临床症状,减少并发症的发生。

Objective To investigate the clinical effect of oseltamivir phosphate combined with Yanhuning in the treatment of children with viral influenza. Methods Sixty patients with viral influenza from March 2016 to December 2018 were conveniently selected. They were randomly divided into two groups, 30 cases in the study group and 30 cases in the control group. The treatment regimen was oseltamivir phosphate oral, the study group added Yanhuning treatment. Comparison 1.The normal temperature of the study group and the control group, the time of cough improvement and the time of cough improvement. 2.The efficacy of viral influenza treatment in children in the study group and control group. 3.Complications during the treatment of the study group and the control group. Results The normal temperature, cough improvement time and cough improvement time of the study group and the control group were significantly shorter than the control group. The results of the two groups were [(2.34±0.85)d,(2.64±0.97)d,(2.12±0.87)d] vs [(3.69±1.15)d,(3.97±1.32)d,(3.66±1.82)d], there were statistically significant differences(t=5.695, 7.415, 5.397, P<0.05);the efficacy of viral influenza treatment in the study group and the control group were 100.00% and 86.67%, respectively. There were differences statistically significant(χ^2=5.377, P<0.05). There was no complication during the treatment of the study group. One case of bronchitis and one case of pneumonia occurred during the hospitalization of the control group. The complication rate of the study group and the control group was 0.00%, 6.67%, there were statistically significant differences(χ^2=6.983, P<0.05). Conclusion The efficacy of oseltamivir phosphate combined with Yanhuning in the treatment of children with viral influenza is positive, which can significantly improve the clinical symptoms of patients and reduce the incidence of complications.