肝硬化疾病诊断中生化检验的应用价值

The Application Value of Biochemical Test in the Diagnosis of Liver Cirrhosis

目的通过对肝硬化患者和健康体检者进行生化检验,探究生化检验对肝硬化疾病诊断的临床应用特点。方法从来该院诊治的2017年1月-2018年8月的肝硬化患者中随机抽取60例患者作为观察组,从同时期健康体检者中随机抽取60名作为对照组,两组研究对象均进行肝功能生化检验,比较两组肝功能生化指标的差异。结果观察组TP值为(62.41±6.45)μmol/L低于对照组(t=24.315,P<0.05),γ-GT值为(177.5±22.01)U/L高于对照组(t=-32.984,P<0.05),DBIL值为(37.24±7.86)μmol/L高于对照组(t=-28.342,P <0.05),ALT值为(92.64±11.51)U/L高于对照组(t=-30.432,P<0.05),PA值为(126.46±85.53)mg/L低于对照组(t=25.487,P<0.05),AST值为(56.49±10.24)U/L高于对照组(t=-33.133,P<0.05),TBIL值为(85.34±7.43)μmol/L高于对照组(t=-41.345,P<0.05),ALB值为(22.45±4.15)g/L低于对照组(t=31.045,P<0.05),CHE值为(2 105.32±753.02)U/L低于对照组(t=36.953,P<0.05)。结论生化检验可以帮助医生了解患者肝功能状况,及时提供具有针对性的预防和治疗措施,为医生提供确诊依据。

Objective To investigate the clinical application characteristics of biochemical tests for the diagnosis of liver cirrhosis by biochemical tests on patients with cirrhosis and healthy subjects. Methods Sixty patients with cirrhosis from January 2017 to August 2018 in our hospital were randomly selected as the observation group. 60 patients from the same period of healthy physical examination were randomly selected as the control group. Liver function biochemical test, comparing the differences in liver function biochemical indicators between the two groups. Results The TP value of the observation group was(62.41±6.45)μmol/L lower than that of the control group(t=24.315, P<0.05), and the γ-GT value was(177.5±22.01)U/L higher than the control group(t=-32.984, P<0.05). The DBIL value was(37.24±7.86)μmol/L higher than the control group(t=-28.342, P<0.05), and the ALT value was(92.64±11.51)U/L higher than the control group(t=-30.432, P<0.05). The PA value was(126.46±85.53)mg/L lower than the control group(t=25.487, P <0.05), and the AST value was(56.49±10.24)U/L higher than the control group(t=-33.133, P<0.05). The TBIL value was(85.34±7.43)μmol/L was higher than the control group(t=-41.345, P<0.05), the ALB value was(22.45±4.15)g/L lower than the control group(t=31.045, P<0.05), and the CHE value was(2 105.32±753.02)U/L was lower than the control group(t=36.953, P<0.05). Conclusion Biochemical tests can help doctors understand the liver function of patients, provide targeted prevention and treatment measures in a timely manner, and provide doctors with a basis for diagnosis.