乳腺包块穿刺细胞学检查与病理诊断的对比

Comparison of Puncture Cytology and Pathological Diagnosis of Breast Masses

目的探讨乳腺包块穿刺细胞学检查与术后石蜡切片病理诊断的临床价值。方法研究对象为168例乳腺包块患者,研究时间为2016年2月—2018年8月,实施穿刺细胞学检查,且与术后石蜡切片病理诊断结果比较,观察乳腺癌阳性预测值、阴性预测值、敏感度、特异度、误诊率、漏诊率及准确率。结果 168例乳腺包块患者经病理诊断后乳腺癌共45例、百分比为26.79%,其他乳腺疾病共123例、百分比为73.21%。经穿刺细胞学检查后阳性例数为43例、阳性预测值为95.56%,阴性例数为121例、阴性预测值为98.37%;与金标准相比,无统计学意义(P> 0.05)。两种方法的敏感度、特异度、误诊率、漏诊率及诊断确诊率相比无统计学意义(P> 0.05)。结论穿刺细胞学检查用于乳腺包块患者中具有较高的临床价值,其中诊断确诊率与术后石蜡切片病理相比无统计学意义,且操作更加简单、方便、实惠、耗时短。

Objective To investigate the clinical value of cytological examination of breast mass and pathological diagnosis of paraffin section after operation. Methods A total of 168 patients with breast mass were enrolled. The study time was from February 2016 to August 2018. The puncture cytology was performed and compared with the pathological diagnosis of paraffin sections. The positive predictive value and negative predictive value of breast cancer were observed. Value, sensitivity, specificity, misdiagnosis rate, missed diagnosis rate and accuracy rate. Results A total of 168 cases of breast masses were diagnosed with pathological diagnosis of breast cancer in 45 cases, the percentage was 26.79%, and other breast diseases were 123 cases, the percentage was 73.21%. After puncture cytology, the number of positive cases was 43 cases, the positive predictive value was 95.56%, the number of negative cases was 121 cases, and the negative predictive value was 98.37%. Compared with the gold standard, there was no statistical significance (P > 0.05). There was no significant difference in sensitivity, specificity, misdiagnosis rate, missed diagnosis rate and diagnostic diagnosis rate between the two methods (P >0.05). Conclusion Puncture cytology has a high clinical value in patients with mammary gland mass. The diagnostic diagnosis rate is not statistically significant compared with postoperative paraffin section pathology, and the operation is simpler, more convenient, more affordable and less time consuming.