心理护理对靶向治疗肠癌患者不良情绪的影响

Psychological Nursing on Targeted Treatment of Depression and Anxiety in Patients With Colorectal Cancer

目的探讨心理护理对接受西妥昔单抗靶向治疗的肠癌患者抑郁、焦虑情绪的影响。方法选取87例2017年5月-2018年5月在本院免费领取中华慈善总会援助的抗结、直肠癌的靶向治疗药物的具有抑郁、焦虑情绪的患者,随机分为两组:对照组44人,采取一般的健康宣教;研究组43人,在一般宣教基础上采取心理护理模式。通过自制表格加PHQ-9、SAS问卷进行对比分析。结果两组患者抑郁、焦虑原始值对比,差异无统计学意义(P>0.05)。实施护理4周、8周、12周后,对照组与研究组患者抑郁、焦虑值均发生一定程度的降低。其中,研究组治疗效果更为显著,且与对照组相比,组间差异均具有统计学意义(P<0.05)。结论心理护理能够缓解接受西妥昔单抗治疗结肠癌患者的不良情绪问题。

Objective Explore the effect of psychological nursing on cetuximab-targeted treatment of depression and anxiety in patients with colorectal cancer. Methods Research subjects with depression were selected from those who received cetuximab in our hospital for free sponsored by China Charity Federation from Jan to Dec 2017. The subjects were randomly divided into two groups: one for Control Group in which 44 subjects took general health education while the other for Research Group in which 43 were treated with psychological care in addition to general health education. The results were compared through self-made forms, PHQ-9 questionnaire and SAS questionnaire. Results There was no significant difference in the original values of depression and anxiety between the two groups (P > 0.05). After 4 weeks, 8 weeks and 12 weeks of nursing, the depression and anxiety values of the control group and the study group decreased to a certain extent. Among them, the treatment effect of the study group is more significant, and compared with the control group, the difference between the groups has statistical significance (P < 0.05). Conclusion Psychological nursing can alleviate negative mood of patients suffering from colorectal cancer treated with cetuximab. It can also improve patients' life quality and prolong their life cycle.