甘精胰岛素联合格列美脲对老年糖尿病的治疗作用研究

The therapeutic effect of insulin glargine and glicmetasone on the treatment of elderly patients with diabetes mellitus

目的探究分析甘精胰岛素联合格列美脲对老年糖尿病的治疗效果。方法将我院收治的86例老年糖尿病患者随机分为观察组和对照组,均为43例,分别采用甘精胰岛素联合格列美脲治疗和甘精胰岛素治疗,对治疗效果展开对比分析。结果治疗前,两组患者FPG、2hPG、HbA1c水平相比差异不明显,P>0.05;治疗后两组患者FPG、2hPG、HbA1c水平明显低于治疗前,且观察组低于对照组,P<0.05;观察组患者治疗后低血糖发生率为2.3%,明显低于对照组患者的18.6%,P<0.05。结论在对老年糖尿病患者治疗时甘精胰岛素联合格列美脲效果较佳,值得推广应用。

Objective To explore and analyze the therapeutic effect of insulin glargine combined with glimepiride on senile diabetes mellitus.Methods 86 elderly patients with diabetes in our hospital were randomly divided into observation group and control group,43 cases were treated with insulin glargine combined with glimepiride and insulin glargine respectively.The therapeutic effects were compared and analyzed.Results Before treatment,there was no significant difference in FPG,2hPG and HbA1c levels between the two groups(P>0.05);after treatment,the levels of FPG,2hPG and HbA1c in the two groups were significantly lower than those before treatment,and those in the observation group were lower than those in the control group(P<0.05);the incidence of hypoglycemia in the observation group was 2.3%,significantly lower than that in the control group(18.6%,P<0.05).Conclusion Insulin glargine combined with glimepiride is effective in the treatment of elderly patients with diabetes mellitus,which is worthy of popularization and application.