清金化痰汤加减治疗痰热阻肺型慢性阻塞性肺疾病急性加重期疗效分析

Therapeutic Effect of Using Qingjin Huayu Decoction in the Treatment of Acute Obstructive Pulmonary Disease with Acute Exacerbation

目的:观察清金化痰汤加减治疗痰热阻肺型慢性阻塞性肺疾病急性加重期的临床治疗效果。方法:选取我院2016年05月~2018年05月收治的92例痰热阻肺型慢性阻塞性肺疾病急性加重期患者为研究对象,随机分为对照组(n=46)和观察组(n=46);给予对照组常规西医治疗,观察组患者加用清金化痰汤加减治疗;对比两组患者临床疗效。结果:治疗后,观察组和对照组患者临床治疗总有效率分别为95.65%(44/46)、76.09%(35/46),两组相比差异具有统计学意义(X^2=7.25,P<0.05)。治疗前,两组患者发热持续时间、中医证候评分、呼吸困难评分及临床肺部感染评分(CPIS)相比均无显著性差异(P>0.05);治疗后,两组患者各指标水平均显著改善,且观察组患者的改善效果均分别显著优于对照组,组间差异具有统计学意义(t=8.22,11.33,11.66,22.87;P<0.05);治疗后,观察组患者FVC、FEV1水平分别为[(2.16±0.32)L]、[(1.67±0.53)L];对照组分别为[(1.93±0.29)L]、[(1.32±0.37)L];两组相比差异显著(t=3.61,3.67;P<0.05)。结论:痰热阻肺型慢性阻塞性肺疾病急性加重期患者在常规西医治疗的基础上加用清金化痰汤加减治疗可以有效的改善患者的临床症状,提高肺功能,效果显著,值得临床推广。

Objective:Analyzing and studying the effect of using Qingjin Huayu Decoction in the treatment of chronic obstructive pulmonary disease during the acute exacerbation of sputum-heat-resistance lung disease.Methods:We selected 92 patients with chronic obstructive pulmonary disease during the acute exacerbation of pulmonary thermal obstruction in our hospital from May 2016 to May 2018 as subjects and were randomly divided into controlled group(n=46)and observation group(n=46),to the controlled group of conventional western medicine treatment,the observation group patients plus Qingjin Huatan Decoction treatment.Compared the clinical efficacy of the two groups of patients.Results:After treatment,the total effective rate of clinical treatment in the observation group and the controlled group was 95.65%(44/46)and 76.09%(35/46),respectively,and the difference between the two groups was statistically significant(X^2=7.25,P<0.05).Before treatment,there was no significant difference in duration of fever,TCM syndrome score,dyspnea score and clinical lung infection score(CPIS)between the two groups(P>0.05).After treatment,the indexes of the two groups were significantly improved,and the improvement effect of the observation group was significantly better than that of the controlled group.The difference between the two groups was statistically significant(t=8.22,11.33,11.66,22.87;P<0.05).After treatment,the levels of FVC and FEV1 were[(2.16±0.32)L]and[(1.67±0.53)L]in the observation group,and[(1.93±0.29)L]and[(1.32±0.37)L,respectively in the controlled group.The difference between the two groups was significant(t=3.61,3.67;P<0.05).Conclusion:Patients with chronic obstructive pulmonary disease during the acute exacerbation of sputum thermal obstruction pulmonary disease in addition to conventional western medicine treatment plus Qingjin Huayu Decoction treatment can effectively improve the patient’s clinical symptoms,improve lung function,the effect is significant,worthy of clinical promotion.