摘要
前庭性偏头痛为眩晕和偏头痛共存的良性复发性眩晕,是引起自发性眩晕发作的常见原因,其发病机制尚不清楚.前庭性偏头痛的家族聚集性提示遗传因素在疾病的发生发展过程中起到一定作用.随着分子遗传学技术的不断发展,与前庭性偏头痛相关的遗传学研究日益成为学者们关注的热点,遗传学研究成果对于进一步探究前庭性偏头痛的病因及病理机制有着重要的意义.本文对前庭性偏头痛相关的遗传学研究及进展加以综述.
The combination of vertigo, dizziness and balance disturbance with migraine is called vestibular migraine, which is frequently reported in clinical neurology. However, the exact pathophysiological mechanisms of vestibular migraine still remain unclear. Familial occurrence of VM has been reported, suggesting a genetic component. With the rapid development of molecular genetic technology in recent decades, the genetic research about vestibular migraine has become a hot topic. The outcomes of molecular genetic studies of vestibular migraine could benefit to unveil the mysterious causes of this disorder. The present review summarized the molecular genetic studies of vestibular migraine.
作者
张静
王秋菊
Zhang Jing;Wang Qiuju(Department of Otorhinolaryngology Head and Neck Surgery,the First Medical Center of People's Liberation Army General Hospital,People's Liberation Army Institute of Otolaryngology,Beijing 100853,China;Department of Otorhinolaryngology of Tianjin Medical University General Hospital,Tianjin 300052,China)
出处
《中华耳鼻咽喉头颈外科杂志》
CAS
CSCD
北大核心
2019年第8期622-625,共4页
Chinese Journal of Otorhinolaryngology Head and Neck Surgery
基金
国家重大科学研究计划项目(2014CB943001)
国家自然科学基金重点项目(81530032,81830028).
关键词
前庭性偏头痛
偏头痛
眩晕
遗传学研究
Vestibular migraine
Migraine disorders
Vertigo
Genetic research
