无症状人群结直肠息肉筛查的风险指标分析

Analysis of clinical risk index for colorectal polyp screening among asymptomatic persons

目的探究无症状人群发生结直肠息肉的风险因素,以便为无症状人群结直肠癌的筛查提供依据。方法选择2016年1月至2018年1月在某医院行肠镜筛查的614例患者,回顾性分析其临床资料,通过单因素连续变量分析息肉组和无息肉组的临床特征,采用Logistic多因素回归分析,得出独立的风险因素。结果614例患者纳入本项研究,其中结直肠息肉组219例,检出率为35.68%。息肉组与无息肉组之间比较,经单因素连续变量分析得出年龄、体重指数(BMI)与无症状人群结直肠息肉相关(P<0.001),男性、幽门螺杆菌(HP)阳性者结直肠息肉检出率高(P<0.05或0.01),Logistic回归分析提示年龄、BMI、HP阳性为结直肠息肉检出的独立危险因素(P<0.05或0.01)。结论男性的结直肠息肉检出率高于女性,年龄越大息肉检出率越高。年龄、BMI、HP阳性是无症状人群结直肠息肉发病的危险因素。

Objective To explore the risk factors of colorectal polyp in asymptomatic persons,so as to provide evidence for colorectal cancer screening among them. Methods 614 patients who underwent colonoscopy screening in a hospital from January 2016 to January 2018 were selected,and their clinical data were analyzed retrospectively.The clinical characteristics of polyp group and non-polyp group were performed by univariate continuous variable analysis,and the independent risk factors were obtained by Logistic multivariate regression analysis. Results 614 patients were enrolled in this study,including 219 patients in colorectal polyp group,with a detection rate of 35.68%.Univariate continuous variable analysis showed that age and body mass index(BMI) were correlated with colorectal polyps in asymptomatic persons between polyp group and non-polyp group( P <0.001).Male and Helicobacter pylori(HP) positive patients had higher detection rate of colorectal polyps( P <0.05 or 0.01).In addition,Logistic regression analysis showed that age,BMI and HP positive were independent risk factors for colorectal polyps( P <0.05 or 0.001). Conclusion The detection rate of colorectal polyps in males is higher than that in females.The older the age,the higher the detection rate of colorectal polyps.Age,BMI and HP positive were risk factors for colorectal polyps among asymptomatic persons.