妊娠时母体子宫淋巴细胞的免疫调节

Immune regulation of maternal uterine lymphocytes during pregnancy

免疫耐受是目前在器官移植等方面最引人关注的问题之一。为维持妊娠的顺利进行,在胚胎着床时,母体子宫要达到感受态并且维持免疫耐受,T细胞、NK细胞在母体子宫内膜淋巴细胞的免疫调节中起重要作用。为研究免疫耐受的机理,主要阐述了妊娠时母体子宫内膜淋巴细胞的调节变化,并对这一研究进展进行了展望。

Immune tolerance is currently the most high-profile factors in organ transplantation.In order to maintain pregnancy smoothly,the process of natural pregnancy need womb during the embryo implantation to feelings state and maintains immune tolerance.The T cells and NK cells in the womb lining lymphocytes play an important role in immune regulation.In order to study the mechanism of immune tolerance,the changes of maternal lymphocyte in uterus during pregnancy were described in this paper.