准分子激光斑块消蚀联合药物涂层球囊处理下肢动脉硬化闭塞症

Excimer laser atherectomy combined with drug-eluting balloon for lower limb arteriosclerosis obliterans

目的评价准分子激光消蚀联合药物涂层球囊对下肢动脉慢性硬化闭塞性病变的疗效。方法回顾性分析2016年9月至2018年12月收治的397例下肢动脉硬化闭塞症患者资料。其中42例患者(42条肢体)接受准分子激光斑块消蚀联合药物涂层球囊扩张治疗。结果42例患者男27例,女15例,平均年龄(65. 7 ±9. 7)岁。平均病变长度(14. 3 ±7. 5)cm,手术技术成功率100%,症状缓解率92. 9%,踝肱指数由术前(0.45 ±0.⑸提高至术后(0. 85 ±0.13)(P =0. 001) o中位随访时间10. 9个月,术后3、6个月和1年的一期通畅率分别为95. 2%、92. 8%和84. 9%,术后1年的保肢率为95. 2%。结论准分子激光斑块消蚀联合药物涂层球囊处理下肢动脉硬化闭塞性疾病近期疗效满意。

Objective To evaluate the efficacy of excimer laser atherectomy ( ELA) combined with drug-coated balloon ( DCB) in the treatment of lower limb arteriosclerosis obliterans. Methods From Sep 2016 to Dec 2018 42 patients (42 limbs) underwent ELA combined with DCB therapy. Results There were 27 males and 15 females. The mean age was (65. 7 ±9. 7 ) years. The average lesion length was ( 14. 3 ±7. 5 ) cm. The technical success rate was 100% and the remission rate of clinical symptoms was 92. 9%. Ankle-brachial index was significantly improved from (0. 45 ± 0. 15 ) pre-operation to (0. 85 ± 0. 13 ) post- operation (P = 0. 001 ). The mean follow-up was 10. 9 months. At 3 , 6, and 12 months follow-up, the primary patency rate was 95. 2%, 92. 8% and 84. 9%. The 1-year limb salvage rate was 95. 2%. Conclusion ELA combined with DCB has a good 1-year results as our data reveal.