X线和MRI在多发性骨髓瘤诊断中的应用价值及影像效果评价

Evaluation on application values and imaging effects of X-ray and MRI in diagnosis of multiple myeloma

目的评价多发性骨髓瘤诊断中X线和MRI的应用价值及影像效果。方法选择我院2016年7月~2018年4月收治的52例多发性骨髓瘤患者作为研究对象,对其临床资料进行回顾性分析,采用的影像学检查方法分别为X线、MRI,分析多发性骨髓瘤的显像特征,并对两种检查方法的诊断结果进行比较。结果X线检查结果显示,52例多发性骨髓瘤患者中病理性骨折13例(25.0%),软组织肿块15例(28.8%),骨质破坏48例(92.3%),骨质疏松14例(26.9%),骨质硬化7例(13.5%);MRI检查结果显示:弥漫加灶型6例(11.5%),局灶型25例(48.1%),弥漫型12例(23.1%),椒盐型10例(19.2%);MRI组对多发性骨髓瘤的检出率、诊断符合率、特异度、敏感度,与X线组相比,X线组均显著低于MRI组,两组差异有统计学意义(P<0.05)。结论MRI对多发性骨髓瘤病变的早期骨髓浸润、骨质破坏情况具有较高的检测价值,相比于X线影像学方法,其检出率和符合率更高,具有临床优先选择和推广价值。

Objective To evaluate the diagnostic values and imaging effects of X-ray and MRI in diagnosis of multiple myeloma. Methods 52 patients with multiple myeloma who were admitted and treated in our hospital from July 2016 to April 2018 were selected as the research objects and their clinical data were retrospectively analyzed. The imaging methods were X-ray and MRI,respectively.The imaging features of multiple myeloma were analyzed and the diagnostic results of the two methods were compared. Results X-ray examination results showed that there were 13 cases(25.0%)with pathological fractures,15 cases(28.8%)with soft tissue mass,48 cases(92.3%)with bone destruction,14 cases with osteoporosis(26.9%)and 7 cases with bone sclerosis(13.5%)in 52 patients with multiple myeloma.MRI results showed that there were 6 cases(11.5%)of diffuse plus foci type,25 cases(48.1%)of focal type,12 cases(23.1%)of diffuse type and 10 cases(19.2%)of pepper-salt type.In the MRI group,the detection rate,diagnostic coincidence rate,specificity and sensitivity of multiple myeloma were significantly higher than those in the X-ray group. The difference between the two groups was statistically significant(P < 0.05). Conclusion MRI has a high detection value for early bone marrow infiltration and bone destruction in multiple myeloma.Compared with the X-ray imaging method,the detection rate and the coincidence rate are higher,which has clinical preference and promotion value.