大气污染对皮肤屏障功能影响的研究进展

Impact of Air Pollution on Skin Barrier Function

近年来,我国大气污染问题日益突出,多地甚至出现严重的雾霾天气,同时全球环境空气污染日益严重,对人类健康构成严重威胁。世界卫生组织(WHO)2017年全球航空状况年度报告提出,世界上90%以上的人口生活在空气不健康的地区,是疾病发生和死亡的主要风险因素,空气污染可直接或间接引起心血管系统、呼吸道系统及生殖系统疾病。大气污染的主要成分为大气颗粒物、臭氧、氮氧化物及二氧化硫等,皮肤作为人体防御功能的第一道屏障,不可避免地直接接触着大气污染物,易受到大气污染的损害。本文初步总结了大气污染物对皮肤屏障功能的影响。

In recent years, the problem of air pollution in our country has become increasingly prominent,even there has been a thick haze in many areas. At the same time, global environmental air pollution is becoming increasingly serious, posing a serious threat to human health. The World Health Organization(WHO) Annual Report on State of Global Air 2017 that over 90% of the world’s population lives in areas with unhealthy air,and is a major risk factor for diseases and death. Air pollution can directly or indirectly cause cardiovascular, respiratory and reproductive system diseases.The main components of air pollution are sulfur dioxide, nitrogen oxides, particulate matter and ozone. The skin, as the first barrier to human defense, Inevitable direct contact with air pollutants, vulnerable to atmospheric pollution damage. This paper summarizes the impact of air pollution on skin barrier function.