外用溃疡散与多西环素片混合粉剂阴道给药治疗支原体阴道炎的疗效观察

目的采用外用溃疡散与多西环素片混合粉剂阴道给药和口服米诺环素治疗支原体阴道炎,探讨中西医结合治疗该疾病的疗效.方法将100例支原体阴道炎患者按照数字随机法分为观察组(同时给予口服盐酸米诺环素和外用溃疡散与盐酸多西环素片混合粉剂阴道给药);对照组(口服盐酸米诺环素),每组各50例,分别给予治疗半个月.同时观察两组患者的支原体转阴率与不良反应.结果观察组患者临床总有效率为96%,对照组患者临床总有效率为46%,差异具有统计学意义(P<0.05).观察组与对照组支原体转阴率及不良反应比较,差异具有统计学意义(P<0.05).结论与单纯西药治疗比较,采用外用溃疡散与多西环素片混合粉剂阴道给药,通过中西医结合治疗支原体阴道炎有较高的临床价值.

Objective To investigate the effect of vaginal administration of mixed powder of ulcer powder and doxycycline tablets for external use and oral minocycline in the treatment of mycoplasma vaginitis. Methods There were 100 patients with mycoplasma vaginitis randomly divided into experimental group(given minocycline hydrochloride orally and mixed powder of topical ulcer powder and doxycycline hydrochloride vaginally)and control group(given minocycline hydrochloride orally),50 cases in each group were given corresponding drug treatment for half a month. At the same time,the negative rate of mycoplasma and adverse reactions were observed. Results The total effective rates were 96% in the observation group and 46% in the control group. The difference was statistically significant(P<0.05).Mycoplasma negative rate and adverse reactions,the observation group compared with the control group, the difference was statistically significant(P<0.05). Conclusion Compared with the treatment of western medicine alone,the combination of traditional Chinese and western medicine,that is,the vaginal administration of topical ulcer powder and doxycycline tablets mixed powder,has great clinical value in the treatment of mycoplasmal vaginitis.