四川遂宁地区不同亚型肠易激综合征患者精神心理、睡眠质量及生活质量差异性分析

Differences in mental and psychological factors,sleep quality and quality of life among patients with irritable bowel syndrome of different subtypes in Suining area of Sichuan Province

目的 探讨四川遂宁地区不同亚型肠易激综合征(IBS)患者精神心理、睡眠及生活质量的差异性。方法 将540例IBS患者分成腹泻型IBS(IBS-D)组225例、便秘型IBS(IBS-C)组180例和混合型(IBS-M)组135例,比较3组患者汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)、匹兹堡睡眠质量指数(PSQI)量表、健康调查简表的评分。结果 IBS-M组患者HAMA及HAMD总评分,焦虑各维度评分、焦虑率、抑郁率及睡眠障碍率均低于其他两组(均P<0.05),生理功能、情感职能、活力、精神健康、社会功能、总体健康方面等生活质量评分高于其他两组(均P<0.05)。结论 四川遂宁地区IBS患者存在一定的心理睡眠障碍,与IBS-M型患者相比,IBS-D、IBS-C患者焦虑抑郁评分及睡眠障碍率更高,生活质量更差。

Objective To explore the differences in mental and psychological factors,sleep quality and quality of life among patients with irritable bowel syndrome(IBS) of different subtypes in Suining area,Sichuan Province.Methods A total of 540 IBS patients were divided into IBS-diarrhea(IBS-D) group(225 cases),IBS-constipation(IBS-C) group(180 cases) and mixed IBS(IBS-M) group(135 cases).The three groups were compared in the scores on the Hamilton Rating Scale for Anxiety(HAMA),the Hamilton Rating Scale for Depression(HAMD),the Pittsburgh Sleep Quality Index(PSQI) scale,and the MOS 36-Item Short-Form Health Survey(SF-36).Results Compared with the other two groups,the IBS-M group got lower total HAMA and HAMD scores,lower score for each domain of anxiety,lower rates of anxiety and depression,and a lower incidence rate of sleep disorders(all P<0.05),as well as higher scores for physiological function,emotional function,vitality,mental health,social function,and general health(all P<0.05).Conclusion IBS patients in Suining area,Sichuan Province,experience a certain sleep disorders concerning mental factors.Compared with patients with IBS-M,patients with IBS-D/IBS-C have higher scores for anxiety and depression,a higher incidence rate of sleep disorders,and poorer quality of life.