幽门螺杆菌补救治疗的研究进展

Advances in rescue therapy of Helicobacter pylori

由于幽门螺杆菌对抗生素耐药率日渐增加等原因,目前幽门螺杆菌的根除率逐步下降,补救治疗是临床医生常常面临的难题。铋剂四联疗法、左氧氟沙星三联疗法、二联疗法、使用新型抑酸剂或联用益生菌等方案均被应用于补救治疗,但并无被普遍接受和认可的“标准方案”,临床实践中更多依赖的是经验治疗,本文对近年来国内外关于幽门螺杆菌补救治疗的研究进展作一综述。

Due to the increasing resistance of Helicobacter pylori to antibiotics, the eradication rate of Helicobacter pylori is gradually decreasing, and rescue therapy is difficult to clinicians. Bismuth quadruple therapy, levofloxacin triple therapy, dual therapy, the use of new acid inhibitors or combination of probiotics has been used in rescue therapy. But there is no universally accepted regimens, Doctors rely more on empirical regimens. In this article, the recent progress in reseach on rescue therapy is briefly reviewed.