布地奈德与丙酸倍氯米松辅助特布他林雾化吸入治疗小儿哮喘急性发作的对比研究

A comparative study of Budesonide and Beclomethasone dipropionate in the treatment of acute asthma attack in children with nebulized inhalation of terbutaline

目的对比小儿哮喘急性发作采用布地奈德与丙酸倍氯米松辅助特布他林雾化吸入治疗的临床疗效。方法于我院收治的小儿哮喘急性发作患儿中选取100例,随机分为2组,2组患儿均行常规对症支持治疗,同时给予其特布他林雾化吸入。在此基础上,甲组患儿辅助布地奈德行雾化吸入治疗,乙组患儿辅助丙酸倍氯米松行雾化吸入治疗,对比2组临床疗效,住院时间与体征消失时间,治疗前后症状体征评分情况。结果甲组患儿治疗总有效率为98%,乙组为98%,差异无统计学意义(P>0.05);2组治疗后症状评分均有所降低,组间对比差异无统计学意义(P>0.05);2组住院时间、肺部哮鸣音消失时间、咳嗽消失时间、呼吸困难消失时间对比,差异无统计学意义(P>0.05)。结论小儿哮喘急性发作采用布地奈德与丙酸倍氯米松辅助特布他林雾化吸入治疗的临床疗效相当。

Objective To analyze the clinical efficacy of budesonide and beclomethasone dipropionate in the treatment of acute asthma in children with nebulized inhalation of terbutaline.Methods From January 2016 to May2018,100 children with acute asthma attack in our hospital were randomly divided into two groups.Both groups received routine symptomatic support and were given special treatment. On the basis of this,the children in group A were treated with budesonide inhalation therapy,and those in group B were treated with nebulized inhalation of beclomethasone dipropionate. The clinical efficacy and hospitalization time of the two groups were compared. And the time of disappearance of signs and the scores of symptoms and signs before and after treatment.Results The total effective rate was 98% in group A and 98% in group B. The difference was not statistically significant(P>0.05).The symptom scores of the two groups were reduced after treatment,but the comparison between groups The difference was not statistically significant(P>0.05).There was no significant difference in the length of hospital stay,the disappearance time of the wheezing sound of the lungs,the disappearance time of cough,and the disappearance time of dyspnea(P>0.05).Conclusion Acute asthma attack in children is equivalent to the clinical efficacy of budesonide and beclomethasone dipropionate in the treatment of terbutaline.