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原发性肝癌合并门静脉癌栓的综合介入治疗的临床效果观察 被引量:6

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摘要 目的:探讨原发性肝癌合并门静脉癌栓的综合介入治疗的临床效果观察。方法:将2015-10~2016-10在我院肿瘤科治疗的82例原发性肝癌合并门静脉癌栓患者随机分为两组,对照组单用经导管肝动脉化疗栓塞术(TACE)治疗,观察组在此基础上使用经皮无水乙醇注射(PEI)及三维适形放疗(3D-CRT),比较两组患者的近期疗效、生存周期、毒副反应。结果:观察组原发性肝癌的治疗有效率为75.62%,明显高于对照组的58.54%(P<0.05);观察组并门静脉癌栓的治疗有效率为85.37%,明显高于对照组的68.29%(P<0.05);观察组治疗后1年、1.5年、2年生存率明显高于对照组,且中位生存期明显长于对照组(P<0.05);观察组恶心呕吐、低热、纳差、乏力、肝功能轻度异常等毒副反应发生率与对照组相比无明显差异(P>0.05)。结论:原发性肝癌合并门静脉癌栓的综合介入治疗的临床效果显著,能有效提升近期疗效,延长生存周期,且安全性高,毒副反应无明显增加,具有积极的临床意义。
出处 《黑龙江医药科学》 2019年第4期167-168,共2页 Heilongjiang Medicine and Pharmacy
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