电针治疗2型糖尿病伴轻度认知功能障碍临床观察

Clinical Observation of ElectropunctureTreatment on Type-Ⅱ Diabetes Mellitus with MCI

目的:观察电针治疗2型糖尿病伴轻度认知功能障碍的临床疗效。方法:选取符合标准的患者60例,随机分为对照组和观察组,每组各30例。对照组在常规生活方式指导的基础上给予口服奥拉西坦胶囊治疗,观察组在对照组治疗的基础上,给予电针治疗,均治疗12周。2组患者采用简易智能状态检查量表(MMSE)评分和蒙特利尔认知评价量表(MoCA)评分评价其治疗前后认知功能的变化情况,同时检测治疗前后空腹血糖(FPG)、早餐后2h血糖(PBG)、及糖化血红蛋白(HbA1c)变化情况。结果:2组患者治疗后MMSE及MoCA评分均显著高于治疗前,且观察组患者治疗后MMSE、MoCA评分均高于对照组治疗后评分,差异均有统计学意义(P<0.05)。2组治疗结束时FPG、HbA1c、PBG低于治疗前,差异均有统计学意义(P<0.05)。结论:电针联合奥拉西坦改善2型糖尿病合并MCI患者的认知功能临床疗效更佳。

Objective: To observe the clinical effectiveness of electropuncture treatment on type-Ⅱ diabetes mellitus with MCI. Methods: select and screen 60 patients who are in line with the research standards and randomly divide them into 2 groups-the control group and observation group with 30 cases in each group respectively. In the control group, patients are treated by orally taking Oxiracetam capsules based on conventional living ways, 800 mg per time, 3 times per day, which lasts for 12 weeks. In the observation group, based on the same treatment in the control group, patients are treated by electropuncture for the same course as that in the control group. Before and after the treatment, the patients in both groups are assessed by MoCA and MMSE respectively in terms of the changes of their cognitive functions. At the same time, the changes of FPG, PBG, and HbA1 c are also tested. Results: MMSE and MoCA scores for the patients after treatment in the two groups are obviously higher than those before treatment and the the MMSE and MoCA scores of patients in the observation group after treatment are obviously higher than those in the control group. The differences are of statistical significance(P<0.05). After the treatment in the two groups, FPG, HbA1 c, and PBG are lower than those before treatment.The differences are ofstatistical significance(P<0.05). Conclusion: the clinical effectiveness of electropuncture treatment accompanied with Oxiracetam capsules on type-Ⅱ diabetes mellitus patients with MCI is better.