辣椒素咳嗽激发试验的临床运用

Clinical application of capsaicin cough challenge test

辣椒素咳嗽激发试验目前广泛运用于临床工作中,是评估咳嗽敏感性的客观指标,试验本身具有很高的安全性和重复性,且操作简便,还可对咳嗽的机制、止咳药物的效果评估及开发有巨大帮助。本研究对辣椒素咳嗽激发试验的临床应用、对咳嗽评估及治疗等方面进行综述。

The capsaicin cough provocation test is the most commonly used test to objectively evaluate cough sensitivity. The mechanism is simple and the test can be accepted by a lot of patients, which could evaluate the degree of cough, guide medicine, promote new drug development, seek for the cause. This article mainly reviews the clinical application of capsaicin cough test to assess degree of cough and guide treatment.