宫腔灌注改善子宫内膜容受性的研究进展

Advanced progress of intrauterine perfusion in improving endometrial receptivity

子宫内膜容受性是胚胎种植的关键,但目前针对子宫内膜容受性尚无公认有效的改善方法。宫腔灌注是当今较新的一种治疗方法,本文通过回顾文献,以宫腔灌注药物为分类,介绍治疗方法,分析作用机制、评判疗效及前景,对宫腔灌注的最新研究进展进行总结。虽然大部分文献表明宫腔灌注可以有效提高子宫内膜容受性,但仍需要更多高质量临床研究证明其有效性,同时也亟需制定规范的诊疗方案与适应证。

Endometrial receptivity is the key to embryo implantation, but there is no recognized effective treatment for patients to improving endometrial receptivity. Nowadays, intrauterine perfusion is a new treatment. Based on reviewing the literature, this paper classifies the drugs of intrauterine perfusion, introduces the treatment approaches, analyzes the mechanism of action, evaluates the curative effect and prospects to summarize the advanced progress of intrauterine perfusion. Although the majority of studies demonstrated that intrauterine perfusion can effectively improve endometrial receptivity, it still needs more high-quality clinical studies to prove their effectiveness. And there is also an urgent need to develop standardized diagnosis and treatment programs, and probe into indication.