Lowering the repeat unplanned revascularization rate after coronary stenting by focusing on the long-term stable control of low-density lipoprotein cholesterol

Patients with coronary artery disease (CAD), after first percutaneous coronary intervention (PCI), often need repeat unplanned percutaneous revascularization due to plaque progression in culprit or non-culprit lesions, including target lesion revascularization (TLR), target vessel revascularization (TVR), and other vessel revascularization (OVR).[1] Low-density lipoprotein cholesterol (LDL-C) levels are controllable and its reduction is integral to reducing major adverse cardiac events after PCI. In this study, active lipid-lowering therapy was widely appreciated early after coronary stenting, showing an initial decline in levels of LDL-C, while its emphasis and recognition was attenuated over time with an increased risk of revascularization due to higher levels of LDL-C.