不同康复训练方案对ADHD患儿症状严重程度及执行功能的影响

Influence of different kinds of rehabilitation training programs on symptom severity,executive function and laboratory parameters of children with ADHD

目的探讨计算机设计下工作记忆和多维执行功能康复训练方案对ADHD患儿症状严重程度、执行功能及实验室指标的影响。方法研究对象选取我院2016年4月~2018年5月收治ADHD患儿共70例,以随机数字表法分为对照组(35例)和试验组(35例),分别采用工作记忆康复训练方案和计算机设计下多维执行功能康复训练方案治疗,比较两组疗效。结果试验组治疗后RS-IV评分、ASQ评分、PHCSS评分及NCT失误率均显著低于对照组治疗后、治疗前(P<0.05);试验组治疗后执行功能量表评分、-100β、25-羟维生素D及PRL水平均高于对照组治疗后、治疗前(P<0.05)。结论相较于工作记忆康复训练方案,计算机设计下多维执行功能康复训练方案用于ADHD患儿治疗能够显著改善相关症状体征,提高认知水平,增强执行功能,并有助于上调S-100β、25-羟维生素D及PRL水平。

Objective To investigate the influence of rehabilitation training programs for working memory and multidimensional execution function under computer design on symptom severity,executive function and laboratory parameters of children with ADHD. Methods 70 children with ADHD were chosen in our hospital in the period from April 2016 to May 2018 and randomly divided into two groups including control group(35 children)with working memory under computer design and experiment group(35 children)with multidimensional execution function under computer design;and the clinical effects of both groups were compared. Results The RS-IV score,ASQ score,PHCSS score and NCT error rate after treatment of experiment group were significant less than control group after treatment and before treatment(P<0.05). The executive function scale score,the levels of S-100 β,25-hydroxyvitamin D and PRL after treatment of experiment group were significant higher than control group after treatment and before treatment(P<0.05). Conclusion Compared with working memory under computer design,multidimensional execution function under computer design in the treatment of children with ADHD can efficiently improve the related symptoms and signs,higher cognitive level,enhance executive function and be helpful to up-regulate the levels of S-100 β,25-hydroxyvitamin D and PRL.