卵巢上皮样恶性间皮瘤一例并文献复习

A Case Report of Ovarian Epithelioid Malignant Mesothelioma and Literature Review

恶性间皮瘤(malignant mesothelioma,MM)是一种临床少见的间皮细胞起源性肿瘤,恶性程度高,原发于胸膜腔较为多见,起源于卵巢极为罕见,术前诊断困难,易与卵巢其他恶性肿瘤、腹膜原发恶性间皮瘤、反应性间皮增生及胃肠道恶性肿瘤相混淆,诊断多依靠术后病理,确诊时多为晚期,预后差,临床医生必须给予足够重视。为了提高对该疾病的认识,现对1例卵巢上皮样恶性间皮瘤患者资料进行分析,回顾复习相关文献,进一步探讨MM的病因、临床组织表现、免疫组化、治疗及预后,加深临床医生对此病的认识,并提高诊断和治疗能力。

Malignant mesothelioma (MM) is a clinically rare mesothelial cell origin tumor with high malignancy. It is more common in the pleural cavity and rare in the ovary. It is difficult to diagnosis before surgery and easy to confused with other malignant tumors of ovary, primary malignant mesothelioma of peritoneum, reactive mesothelioma and malignant tumors of gastrointestinal tract, therefore the diagnosis mostly depends on the postoperative pathology and is usually late with poor prognosis, to which clinicians must pay enough attention. In order to improve the understanding of the disease, we now analyze the data of a patient with ovarian epithelioid malignant mesothelioma, review the relevant literatures, and further explore the etiology, clinical tissue performance, immunohistochemistry, treatment and prognosis of MM to deepen the clinician understanding of the disease and improve the ability of diagnosis and treatment.