普米克令舒、硫酸特布他林雾化液及沐舒坦联合治疗毛细支气管炎的临床观察及对患者C-反应蛋白的影响

Clinical Observation of Pulmicort Resuscitation with Terbutaline Sulphate Solution for Nebulization and Mucosolvan in Treatment of Bronchiolitis and Its Effect on C-reactive Protein in Patients

目的:探讨普米克令舒、硫酸特布他林雾化液及沐舒坦联合治疗毛细支气管炎的临床效果及对患者C-反应蛋白的影响。方法:选取2017年10月-2019年1月笔者所在医院收治的毛细支气管炎患儿160例,按照随机数字法分为对照组和研究组,各80例,对照组在常规化痰治疗的基础上联合氨茶碱,研究组在常规治疗的基础上联合普米克令舒、硫酸特布他林雾化液及沐舒坦,对两组患儿治疗不同时间内心率、呼吸频率、炎症因子水平及临床治疗效果进行比较。结果:两组患儿治疗前及治疗后6 h内心率、呼吸频率比较差异无统计学意义(P>0.05),但均优于本组治疗前(P<0.05);治疗结束后研究组患儿炎症因子水平明显低于对照组,研究组患儿临床总有效率显著高于对照组,差异均有统计学意义(P<0.05)。结论:小儿毛细支气管炎采用普米克令舒、硫酸特布他林雾化液及沐舒坦联合治疗,可有效提高临床疗效,降低炎症因子水平。

Objective:To investigate the clinical observation of Pulmicort Resuscitation,Terbutaline Sulphate Solution for Nebulization and Mucosolvan in treatment of bronchiolitis and the effect on C-reactive protein.Method:A total of 160 children with bronchiolitis admitted to our hospital from October 2017 to January 2019 were randomly divided into the control group and the research group,80 cases in each group.The control group was treated with Aminophylline on the basis of routine phlegm resolving therapy,while the research group was treated with Pulmicort Resuscitation,Terbutaline Sulphate Solution for Nebulization and Mucosolvant on the basis of routine treatment.Heart rate,heart rate and heart rate of the two groups were compared at different time.Respiratory frequency,levels of inflammatory factors and clinical efficacy were compared.Result:There was no significant difference in heart rate and respiratory rate between the two groups before and 6 hours after treatment(P>0.05),but they were better than those before treatment(P<0.05).After treatment,the level of inflammatory factors in the control group was significantly higher than that in the research group(P<0.05).The clinical effective rate of the study group was significantly higher than that of the control group(P<0.05).Conclusion:Pulmicort Resuscitation,Terbutaline Sulphate Solution for Nebulization and Mucosolvan can effectively improve the clinical efficacy and decrease the level of inflammatory factors.