丙种球蛋白冲击治疗急性病毒性心肌炎的有效性和安全性

Efficacy and safety of gamma globulin impact therapy on acute viral myocarditis

目的分析丙种球蛋白冲击治疗急性病毒性心肌炎的有效性和安全性。方法选择我院收治的92例急性病毒性心肌炎患儿,采用电脑随机法将其分为观察组和对照组,每组46例。对照组采取常规治疗,观察组在此基础上行丙种球蛋白冲击治疗。比较两组的治疗效果。结果治疗1个月后,两组患儿CK、CK-MB、LDH水平均降低,且观察组低于对照组(P<0.05);治疗3个月后,观察组心电图ST-T正常占比、心律失常治愈率均高于对照组(P<0.05);观察组的治疗总有效率高于对照组(P<0.05)。结论丙种球蛋白冲击治疗急性病毒性心肌炎患儿效果显著,可改善心肌酶谱水平,且安全性较好。

Objective To analyze the efficacy and safety of gamma globulin impact therapy on acute viral myocarditis. Methods A total of 92 children with acute viral myocarditis admitted in our hospital were selected and divided into observation group and control group by computer random method, with 46 cases in each group. The control group received routine treatment, and the observation group received gamma globulin impact therapy on this basis. The therapeutic effects of the two groups were compared. Results After one month of treatment, the levels of CK, CK-MB and LDH in the two groups decreased, and those in the observation group were lower than the control group (P<0.05). After 3 months of treatment, the proportion of children with normal ST-T in ECG and the cure rate of arrhythmia in the observation group were higher than those in the control group (P<0.05). The total effective rate of treatment in the observation group was higher than that in the control group (P<0.05). Conclusion Gamma globulin impact therapy for acute viral myocarditis in children has a significant effect, which can improve the levels of myocardial enzyme, with good safety.