颈动脉斑块与糖尿病视网膜病变的关系

The relationship between carotid plaque and diabetic retinopathy

目的探究糖尿病患者的颈动脉斑块与糖尿病视网膜病变的关系。方法选取2015年9月至2018年9月在我院接受治疗的126例糖尿病视网膜病变患者为观察组,另选取同期在我院接受治疗的78例无视网膜病变的2型糖尿病患者作为对照组。收集患者的性别、年龄、糖尿病病程等临床资料,分析糖尿病患者视网膜病变的独立危险因素。结果观察组的平均年龄、糖化血红蛋白、中央视网膜厚度降低及颈动脉斑块患者占比明显高于对照组,差异具有统计学意义(P<0.05)。Logistic回归分析结果显示,中央视网膜厚度降低与颈动脉斑块是糖尿病患者视网膜病变的独立危险因素(P<0.05)。结论颈动脉斑块是糖尿病患者发生视网膜病变的独立危险因素,对糖尿病视网膜病变具有较高的诊断价值。

Objective To explore the relationship between carotid plaque and diabetic retinopathy in diabetic patients. Methods A total of 126 patients with diabetic retinopathy who were treated in our hospital from September 2015 to September 2018 were selected as observation group, and another 78 type 2 diabetes patients without retinopathy who were treated in our hospital during the same period were selected as control group. The clinical data as patients' gender, age and course of diabetes were collected, and the independent risk factors of diabetic retinopathy were analyzed. Results The average age, glycosylated hemoglobin, the percentage of patients with decrease of central retinal thickness and carotid plaque in the observation group were significantly higher than those in the control group, and the differences were statistically significant (P<0.05). Logistic regression analysis showed that decreased central retinal thickness and carotid plaque were independent risk factors for diabetic of retinopathy (P <0.05). Conclusion Carotid artery plaque is an independent risk factor for diabetic retinopathy and has high diagnostic value for diabetic retinopathy.