分析胰岛素泵皮下注射和多次胰岛素皮下注射治疗妊娠期糖尿病患者的临床效果

Analysis of the clinical effect of insulin pump subcutaneous injection and multiple insulin subcutaneous injection in treatment of gestational diabetes mellitus

目的研究分析胰岛素泵皮下注射和多次胰岛素皮下注射治疗妊娠期糖尿病患者的临床效果。方法随机抽取了2015年7月至2017年7月间本院住院部收治的100例妊娠期糖尿病患者作为研究对象,将这100例患者进行了分组处理,即参照组以及研究组。两组各50例患者,分别采用不同的方法对其进行治疗。参照组患者接受多次胰岛素皮下注射治疗,研究组患者接受胰岛素泵皮下注射治疗,比较两组患者临床治疗效果。结果治疗后研究组患者空腹血糖(FPG)、餐后2 h血糖(P2hPG)指标水平及胰岛素使用量均显著低于参照组,糖化血红蛋白(HbA1c)水平显著高于参照组(P<0.05);两组患者治疗后均有不良事件发生,包括早产、巨大儿、低血糖及产后出血,研究组总发生率比参照组显著更低(P<0.05)。结论妊娠期糖尿病的临床治疗中,采用胰岛素泵皮下注射方法的效果优于常规治疗手段。胰岛素泵皮下注射还有利于降低不良事件发生率,安全性更高,值得推广。

Objective To study and analyze the clinical effect of insulin pump subcutaneous injection and multiple insulin subcutaneous injection in treatment of gestational diabetes mellitus. Methods 100 cases of patients with gestational diabetes mellitus and who treated in our hospital of Inpatient Department from July 2015 to July 2017 were randomly selected as the research objects,and 100 cases of patients were divided into two groups, the reference group and the study group,with 50 cases in each group,and were treated with different methods.The reference group were received multiple subcutaneous insulin injections,while the study group were received subcutaneous insulin pump injection.Then, the clinical effects of two groups of patients were compared. Results After the treatment, the levels of fasting blood glucose(FPG), postprandial 2-hour blood glucose(P2 h PG) and insulin use in the study group were significantly lower than those in the control group, and the levels of glycosylated hemoglobin(Hb A1 c) were significantly higher than those in the control group(P<0.05).The adverse events were occurred of two groups after treatment,which including premature birth, macrosomia, hypoglycemia and postpartum hemorrhage. And the total incidence in the study group was significantly lower than that in the control group(P<0.05). Conclusion In the clinical treatment of gestational diabetes mellitus, the effect of insulin pump subcutaneous injection is better than that of routine treatment, and the subcutaneous injection of insulin pump is also helpful to reduce the incidence of adverse events and has higher safety, thus it is worth promoting.