中西医结合治疗病毒性肝炎重度黄疸临床分析新探

Clinical Analysis of Severe Jaundice of Viral Hepatitis Treated by Integrative traditional Chinese and Western Medicine

目的探讨对病毒性肝炎重度黄疸患者采取中西医结合治疗的临床效果。方法抽取该院在2017年10月-2018年10月所收治的76例病毒性肝炎重度黄疸患者作为该次实验的研究主体,将其按照数字随机表法分为单纯组和综合组,每组分别为38例患者。单纯组仅采取单一的西药进行治疗,综合组则在单纯组的基础上加以中药进行联合治疗,收集并统计单纯组和综合组患者的各项临床资料,并且对比两组患者的治疗有效率、治疗前后总胆红素水平和丙氨酸转氨酶水平的变化情况以及肝功能恢复时间。结果综合组的治疗有效率36例(94.74%)显著高于单纯组28例(73.68%),差异有统计学意义(χ2=6.333,P=0.012);治疗后综合组的总胆红素水平以及丙氨酸转氨酶水平均低于单纯组,差异有统计学意义(t=17.431、9.893,P=0.000、0.000);综合组的丙氨酸转氨酶恢复正常时间以及退黄时间均明显短于单纯组,差异有统计学意义(t=6.476、5.480,P=0.000、0.000 <0.05)。结论对病毒性肝炎重度黄疸患者采取中西医结合治疗的方式,对于改善患者的肝功能效果更加显著,利于提高整体治疗效果。

Objective To investigate the clinical effect of integrated Chinese and Western medicine on patients with viral hepatitis with severe jaundice. Methods Seventy-six patients with severe jaundice with viral hepatitis admitted to our hospital from October 2017 to October 2018 were enrolled as the main subjects of this experiment. They were divided into simple group and comprehensive group according to the numerical random table method, 38 cases in each group. The simple group was treated with western medicine. The comprehensive group was treated with traditional Chinese medicine on the basis of the simple group. The clinical data of the simple group and the comprehensive group were collected and counted. The treatment efficiency, changes in total bilirubin levels and alanine aminotransferase levels before and after treatment, and the recovery time of liver function of the two groups were compared. Results The treatment efficiency of the comprehensive group(36 cases, 94.74%) was significantly higher than that in the simple group(28 cases, 73.68%),the different was statistically signifcant(χ2=6.333, P=0.012). After treatment, total bilirubin level and alanine aminotransferase in the comprehensive group were lower than those of the simple group,the different was statistically signifcant(t=17.431, 9.893, P=0.000, 0.000). The alanine aminotransferase recovery time and the yellowing time of the comprehensive group were significantly shorter than those in the simple group,the different was statistically signifcant(t=6.476, 5.480, P=0.000, 0.000). Conclusion The combination of traditional Chinese and western medicine for patients with severe jaundice with viral hepatitis is effective in improving the liver function, which is beneficial to improve the overall treatment effect.