糖皮质激素与手术在肉芽肿性乳腺炎治疗中的应用分析

Analysis of the application of Glucocorticoids and Surgery regimen in Granulomatous Mastitis

目的:探讨糖皮质激素与手术治疗的不同模式在肉芽肿性乳腺炎治疗中的疗效。方法:本研究采用回顾性分析的研究方法,选取南平市第一医院乳腺外科2014年7月~2016年9月收治的肉芽肿性乳腺炎患者62例。根据治疗方案分为三组。A组:口服糖皮质激素治疗3~6个月;B组:口服糖皮质激素治疗1~2个月后行手术治疗,术后口服糖皮质激素治疗1个月;C组:诊断后直接手术治疗,术后口服糖皮质激素治疗3个月。分析比较三组治愈率、复发率及外形满意程度。结果:B组的治愈率明显高于A组和C组,差异有统计学意义(P<0.05);A组和B组的外形满意率明显高于C组,差异有统计学意义(P<0.05)。结论:糖皮质激素+手术+糖皮质激素方案治疗肉芽肿性乳腺炎的治愈率高,复发率低,外形满意度高,值得临床推广。

Objective:To investigate the efficacy of different modes of glucocorticoid and surgical treatment in the treatment of patients with granulomatous mastitis. Methods:This study used retrospective analysis of 62 patients with granulomatous mastitis admitted to the Department of Breast Surgery, Nanping First Hospital from July 2014 to September 2016. According to the treatment plan, it is divided into three groups. Group A: oral glucocorticoid treatment for 3~6 months;group B: oral glucocorticoid treatment for 1~2 months after surgery, oral glucocorticoid treatment for 1 month;group C: direct surgery after diagnosis Treatment, oral glucocorticoid treatment for 3 months. The cure rate, recurrence rate and shape satisfaction of the three groups were analyzed and compared. Results:The cure rate of group B was significantly higher than that of group A and group C(P<0.05). The satisfaction rate of group A and group B was significantly higher than that of group C (P<0.05). Conclusion:Glucocorticoid + surgery + glucocorticoid regimen has a high cure rate, low recurrence rate and high shape satisfaction, which is worthy of clinical promotion.