缓慢性心律失常的发病机制及中西医治疗现状

Mechanism of Bradyarrhythmia and Current Traditional Chinese and Western Medicine Treatment

缓慢性心律失常(BA)是一类以心率减慢为特征的临床疾病,发病机制复杂,涉及心肌细胞离子通道基因变异、离子通道功能异常、自主神经系统功能异常、心肌组织病变等。西医治疗手段以植入起搏器为主,近年来中药在治疗BA方面也有确切的临床疗效。中医理论认为,BA的根本病机在于心肾阳虚,不同辨证分型治法不同。中药安全性较高,协同现代西医治疗方法治疗BA,不仅肯定了西医治疗的快速性和中药治疗的安全性,还为BA的临床研究提供了新思路。

Bradyarrhythmia(BA) is a kind of clinical disease characterized by descent of heart rate.Its pathogenesis is complex,involving gene mutation of ion channels in cardiomyocytes,abnormal function of ion channels,abnormal function of autonomic nervous system,myocardial pathological changes and so on.Pacemaker implantation is the main treatment method of western medicine.In recent years, Chinese medicine has definite clinical effect in the treatment of BA.According to the theory of traditional Chinese medicine,the basic pathogenesis of BA is deficiency of heart and kidney yang.According to its syndrome differentiation and classification,the treatment is different.The safety of traditional Chinese medicine is relatively high.As a synergistic treatment of modern western medicine,it not only affirms the rapidity of western medical treatment and the safety of traditional Chinese medicine treatment,but also provides a new idea for the clinical research of BA.