铁代谢与2型糖尿病关系的研究进展

Analysis of Correlation between Iron Metabolism and Type 2 Diabetes Mellitus

糖尿病是一组以高血糖为主要特征的常见代谢性疾病,可分为1型糖尿病、2型糖尿病、妊娠糖尿病及特殊糖尿病4种类型,其中2型糖尿病受多种因素的影响,且不同因素之间相互作用、相互影响。铁是人体必需的重要微量金属元素之一,维持机体内铁状态的稳定对于保证机体正常的生理活动具有重要的临床意义。此外,血清铁、血清铁蛋白、血清转铁蛋白、尿转铁蛋白在机体内的水平能够影响2型糖尿病的发病,与2型糖尿病的发生、发展密切相关。

Diabetes mellitus is a group of common metabolic diseases characterized by hyperglycemia.It can be divided into four types:type 1 diabetes mellitus,type 2 diabetes mellitus,gestational diabetes mellitus and special diabetes mellitus.At present,it is generally believed that the onset of type 2 diabetes is related to many different factors,which can interact with and influence each other.Iron is one of the essential trace metal elements for human body.Maintaining the stability of iron status in the body has important clinical significance for ensuring normal physiological activities of the body.In addition,the high levels of serum iron,serum ferritin,serum transferrin and urinary transferrin can affect the onset of type 2 diabetes,which can be described as closely related to the occurrence and development of type 2 diabetes mellitus.