早期非小细胞肺癌淋巴结转移规律及清扫方式研究进展

Advances in Lymph Node Metastasis and Lymph Node Dissection in Early Non-small Cell Lung Cancer

肺癌是目前我国发病率和死亡率均居首位的恶性肿瘤,其中以非小细胞肺癌为主要病理类型。淋巴结转移是非小细胞肺癌最常见和最主要的转移途径,也是影响肺癌分期和预后最重要的因素。由于目前通过现有手段术前很难准确判断早期非小细胞肺癌患者的淋巴结受累情况。因此,在早期非小细胞肺癌中,尤其是在临床I期非小细胞肺癌患者中,淋巴结清扫方式一直存在很大争议。本文就非小细胞肺癌淋巴结转移的规律及清扫方式进行综述。

Lung cancer is the malignant tumor with the highest morbidity and mortality in China. Non-small cell lung cancer is the main pathological type. Lymph node metastasis is the most common and primary metastatic pathway in nonsmall cell lung cancer. Acknowledged as the major factor determining tumor staging and prognosis. Unfortunately, it’s presently hard to make an accurate preoperative judgment on the lymph node metastasis of early stage non-small cell lung cancer. Consequently, there has been a long-standing controversy on lymph node sweeping for early stage non-small cell lung cancer, especially for those clinical stage I. The regularity of non-small cell lung cancer lymph node metastasis and the ways of lymph node sweeping will be reviewed in this paper.