摘要
目的:探讨联用胰岛素和西格列汀对老年2型糖尿病患者进行治疗的临床效果.方法:将2017年1月至2019年1月期间西安交通大学第一附属医院收治的200例老年2型糖尿病患者作为研究对象.将这200例患者分为对照组和研究组,其中对照组有90例患者,研究组有110例患者.为对照组患者使用诺和灵N和二甲双胍进行治疗,为研究组患者使用诺和灵N和西格列汀进行治疗.治疗3个月后,比较两组患者的各项血糖指标和不良反应的发生率.结果:经过3个月的治疗,与对照组患者相比,研究组患者空腹血糖的水平、餐后2 h血糖的水平、糖化血红蛋白的水平和不良反应的发生率均更低,P<0.05.结论:联用胰岛素和西格列汀对老年2型糖尿病患者进行治疗的效果显著,可有效地调节其血糖的水平,降低其不良反应的发生率.
Objective: To investigate the clinical effect of combined insulin and sigliptin in the treatment of elderly patients with type 2 diabetes. Methods: a total of 200 elderly patients with type 2 diabetes admitted to the first affiliated hospital of xi ‘an jiaotong university from January 2017 to January 2019 were studied. The 200 patients were divided into control group and research group, of which 90 patients were in the control group and 110 in the research group. Patients in the control group were treated with novorin N and metformin, and patients in the study group were treated with novorin N and siglitine. After 3 months of treatment, blood glucose indexes and incidence of adverse reactions were compared between the two groups. Results: after 3 months of treatment, compared with the control group, the fasting blood glucose level, postprandial blood glucose level, glycosylated hemoglobin level and the incidence of adverse reactions in the study group were all lower (P < 0.05). Conclusion: the combination of insulin and sigliptin has a significant effect on the treatment of elderly patients with type 2 diabetes, which can effectively regulate their blood glucose level and reduce the incidence of adverse reactions.
作者
王晶
崔巍
张田
Wang Jing;Cui Wei;Zhang Tian(Xi'an jiaotong university, xi'an Shanxi 710061;Department of gerontology, the first affiliated hospital of xi'an jiaotong university, xi'an Shanxi 710061;Department of oncology, xianyang first people's hospital, xianyang Shanxi 712000)
