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美托洛尔联合氯吡格雷对ST段抬高性心肌梗死PCI患者术后左心功能的影响 被引量:8

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摘要 目的探究美托洛尔联合氯吡格雷对ST段抬高性心肌梗死经皮冠状动脉介入术(PCI)患者术后左心功能的影响。方法选取2017年1月-2018年12月我院收治的ST段抬高性心肌梗死PCI术后的患者160例,按随机数字表法将其分为对照组(n=80)和观察组(n=80)。对照组给予PCI术后常规抗凝治疗,观察组在此基础上联合美托洛尔治疗。比较2组患者治疗前后心功能指标、血凝状态、TIMI分级情况。结果与治疗前比较,治疗后两组患者LVESV、LVEDV水平均显著降低,且观察组显著低于对照组(P<0.01);LVEF、E/A水平均显著升高,且观察组显著高于对照组(P<0.01);与治疗前比较,治疗后两组患者FIB、D-D水平均显著降低,且观察组显著低于对照组(P<0.01);与治疗前比较,治疗后2组患者TIMI血流分级0~2级比例均显著降低,且观察组显著低于对照组(P<0.01),3级比例显著增高,且观察组显著高于对照组(P<0.01)。结论美托洛尔联合氯吡格雷可有效改善ST段抬高性心肌梗死PCI患者术后心功能,降低血凝状态有效改善血流动力学,值得临床推广应用。
出处 《解放军预防医学杂志》 CAS 2019年第8期145-146,149,共3页 Journal of Preventive Medicine of Chinese People's Liberation Army
基金 江苏省科技计划基金资助项目(BL201223)
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